If Chelsea lose this one, they could slip to third and would head to Valencia knowing they realistically need to win to progress.
Pulisic is in Chelsea's starting lineup with Dest beginning on the bench for Ajax. He pulled off a stunning save in the dying stages of the match to see the club emerge with all the three points from the encounter, a save which saw which grow in stature as a goal-keeper.
"So hopefully now we can bring that form back to Stamford Bridge".
Tammy Abraham scored an own goal with just two minutes played after Quincy Promes floated in a risky ball into the box.
Ajax forward Quincy Promes, who has also impressed for the Eredivise side this season, regained the lead for the away side with 20 minutes on the clock. Oxlade-Chamberlain restored Liverpool's lead in the 53rd minute.
Hakim Ziyech's cross hits Kepa square in the face and goes in.
Chelsea were late to their own UEFA Champions League party with Ajax on Tuesday, helplessly headed for outright embarrassment by an irresistible side on their own field before busting the door down and turning it into Party of the Year at Stamford Bridge.
The Blues would require one other "coming of age" show to fend off Ajax - can they ship?
"Due to the important of the game, we have to play a much better match".
Ajax then lost Daley Blind and Joel Veltman, both to second bookable offences.
While most teams would have rolled over and given up at 4-1 down, Lampard's side kept pressing, kept attacking and should be given huge plaudits for their efforts.
What a moment for Reece James!
Chelsea captain Cesar Azpilicueta started the come back, tapping home from close range to make it 4-2.
Chelsea's appeal against a two-window transfer ban imposed by Federation Internationale de Football Association is due to come before the Court of Arbitration for Sport on November 20.
But Chelsea did experience one blow during their exemplary second-half display.
However, Mount took a nasty-looking knock in the second 45 vs Ajax and had to be withdrawn. "And I think it needs to be a really open conversation - referees, managers, fans".