Little is now serving three life sentences on California convictions, and in 2019, received two additional sentences for 15 years to life for the murders of two women in Cincinnati.
The Federal Bureau of Investigation has confirmed a 79-year-old man as the most prolific serial killer in USA history. Investigators have confirmed 50 of those murders and are seeking information to confirm the rest of Little's confessions.
In a news release on Sunday, the FBI announced that federal crime analysts believe all of his confessions are credible, and officials have been able to verify 50 confessions so far. "Even though he is already in prison, the Federal Bureau of Investigation believes it is important to seek justice for each victim-to close every case possible". Some of the bodies have never been discovered, and some of the cases were originally ruled overdoses or accidental.
Law enforcement is still working to verify the remaining 43 cases he confessed to.
Little often targeted vulnerable women involved in prostitution and addicted to drugs.
Little was arrested in 2012 and extradited to California on a narcotics charge.
Numerous murders that he has confessed to bear similarities to those of Carol Alford, 41, Audrey Nelson, 35, and Guadalupe Apodaca, 46 - the three women he was originally convicted of killing and sentenced to three terms of life with no parole.
The 3rd district state attorney's office says a Taylor County grand jury indicted Little in April for the death of Ruby Lane 26 years ago.
In another video he admitted to strangling a woman to death in North Little Rock, Arkansas, between 1992 and 1994.
His murders went undetected for almost half a century until Texas ranger James Holland developed a hunch about his guilt.
You can access a list of Little's unmatched confessions here. He confessed to slaying an unidentified white woman in 1970 or 1971 in Homestead and another woman killed in 1971 or 1972, who possibly worked on Homestead Air Force Base. Until 2014, however, he had managed to avoid a conviction for murder, and had served less than a total 10 years in prison.
The FBI is now appealing for help in identifying all of his victims.
Authorities in Knox County, Tennessee, said Monday that a woman named Martha Cunningham was likely a victim of Little's.
That's three times the number of victims Ted Bundy confessed to killing. They say Little agreed to talk to them because he was hoping to move prisons.