Trump, 73, appeared to have turned on his network of choice via Twitter on Wednesday, as he unleashed an angry pair of tweets criticizing Fox for Sandra Smith's interview with Democratic National Committee communications director Xochitl Hinojosa.
He called Fox "HOPELESS & CLUELESS" and said "they should go all the way LEFT and I will still find a way to Win - That's what I do, Win".
"We don't work for you", Fox News contributor Guy Benson tweeted, adding: "My job isn't to reinforce exactly what partisans want to hear".
A Fox News spokesman did not immediately respond to a request for comment on Trump's tweets.
In that tweet, Mr. Trump alleged Smith's show was the lowest rated on Fox News. Other recent Twitter targets of Trump's ire include "The Five" co-host Juan Williams, ("always nasty and wrong), "Fox News Sunday" moderator Chris Wallace ("Fox is moving to the losing side") and afternoon anchor Shepard Smith ("Fake News CNN is better")".
In the past Trump has promoted a much smaller conservative channel, OANN, which has positioned itself as a friendlier network to Trump. Too Bad! I don't want to Win for myself, I only want to Win for the people, ' he continued.
"I'm not happy with Fox", Trump told Brian Kilmeade on the "Fox & Friends" host's radio show Thursday.
Fox News has been taking a turn to the Left over the past few years, as some people have pointed out.
'The New @FoxNews is letting millions of GREAT people down! Fox isn't working for us anymore!'
Trump has long sung the praises of Fox News programs such as Fox and Friends, but has targeted the network before, though without the intensity and frequency he has applied to other outlets, including CNN and the New York Times.
While Mr Trump routinely lashes other networks as "fake news", he or his top aides make nearly daily appearances to give often softball interviews on Fox. In response, the network's "Special Report" host Bret Baier said on-air, "Fox has not changed". Joe Biden, Elizabeth Warren, Bernie Sanders and Kamala Harris all beat him in hypothetical head-to-head matchups, an outcome that White House aides said infuriated the president behind the scenes.
In the wake of the president's latest online tantrum, the Washington Post's Aaron Blake, a senior political reporter, hypothesized that Trump appears to be "applying increasing pressure on the network and apparently hoping it yields even more favorable coverage".
"Given the fine margins Trump is dealing with in his reelection campaign, Fox News could help sink him". "You could even make an argument that Trump needs Fox more than Fox needs Trump".
Watch above, via Fox News.