The storms caused debris so thick that at one point, highway crews had to use snowplows to clear an interstate highway.
The National Weather Service warned there was a risk of more tornadoes and hailstorms from Tuesday afternoon into the night in Kansas and other Midwest states, while residents in Arkansas and Oklahoma braced for more record-breaking floods.
In Indiana, at least 75 homes were damaged in Pendleton and nearby Huntsville, said Todd Harmeson, a spokesman for Madison county emergency management, though no serious injuries were reported, . Isolated tornadoes or large hail can't be ruled out. More than 50,000 people without electricity.
"We've had injuries ranging form lacerations to bumps and bruises from folks being thrown around in their houses due to the storms", she said.
A tornado with winds up to 140 mph (225 kph) struck near Trotwood, Ohio, eight miles (12 kilometers) from Dayton, and Mayor Mary McDonald reported "catastrophic damage" in the community of 24,500. OH is accustomed to storms during tornado season, but Monday night's tornado cluster was out of the ordinary because of its strength, he says. It completely leveled homes and entire buildings, leaving over 80,000 people without power, and affecting more than 5 million. Tornadoes will be possible in a brief window from late afternoon through early evening in southwest Iowa to the I-35 line and possibly near the Des Moines Metro.
Damaged homes and debris mark the path of a tornado in Celina, Ohio. He added at least six people had been injured, although none seriously.
In Montgomery County, which includes Dayton, Sheriff Rob Streck said many roads were impassable.
The weather service said it will be conducting damage surveys over the next few days in multiple areas throughout the state, including Dayton. Arkansas, Oklahoma and Missouri have all activated National Guard units to respond to the storms.
If we do see severe weather all types will be possible including hail, damaging wind, heavy rain and even a few tornadoes, especially near that warm front.