When George County sheriff's deputies responded to the home for a report of domestic assault, the report said McLeod opened the door with a glass of alcohol in his hand and said, "Are you kidding me?" McLeod, 58, was charged with misdemeanor domestic violence and is free on $1,000 bail, but he's apparently not taking many calls.
Republican House Speaker Philip Gunn said that McLeod should step down if he did assault his wife.
"These actions are unacceptable for anyone", Gunn said.
Investigators said the state lawmaker "had slurred speech and walked slow in a zigzag pattern".
McLeod's wife reportedly told the police that her husband "just snapped" and that this is common when he drinks alcohol. In the description, deputies said he was so intoxicated he had to grab a handrail to maintain his balance.
According to a statement from McLeod's wife, he had become angry because he wanted to have sex and punched her when he determined that she was not undressing quickly enough.
Police reported finding blood on the couple's bed and bedroom floor.
McLeod, who has served in Mississippi's House since 2012, co-sponsored a bill this year to ban abortions when a fetal heartbeat is detected - which usually happens about six weeks into pregnancy.
Deputies said that when they arrived, they could hear McLeod yelling through the door, "the cops are here!" The woman said McLeod started banging on the door and threatened to "kill her (expletive) dog" if she didn't open it, according to the Sun Herald.
Sen. David Blount, D-Miss., tweeted Tuesday, "Rep. McLeod should resign".
McLeod's wife did not want go to the hospital by ambulance, but assured authorities she'd have her daughter take her to get checked so authorities would have a report of the injuries.
McLeod faces re-election later this year, but is now running unopposed.