She arrived at court holding the hand of her brother Moore Huffman Jr. and did not say anything to journalists.
Her husband, Fargo star William H Macy, was not with her in court.
"No, your honour", Huffman replied.
Huffman did not dispute the facts stated by the government, but she clarified that her daughter had received extra time on tests since first seeing a neuropsychologist at age 8. "This transgression toward her and the public I will carry for the rest of my life".
Prosecutors are recommending four-months of prison time for the actress, a fine of $20,000, and twelve-months of supervised release. He is scheduled to be sentenced September 19. Seventeen other parents, including Loughlin, have chose to fight the charges and formally submitted not guilty pleas. "Everything else (prosecutors) said I did, I did".
The case has put the career of the Emmy-winning actor in turmoil and laid bare the elite's ability to influence the education system.
The charges stem from Huffman's role in the still ongoing college admissions scandal that has ensnared various people in the world of entertainment and business.
Huffman has already publicly apologized and stated that he daughter was not aware of her actions.
She has apologised, expressing "deep regret and shame", and said her 18-year-old daughter was unaware of her actions.
- Manny Medrano, a defense attorney and former federal prosecutor, told The Times last month that based on 2019 federal sentencing guidelines, Huffman likely would face from four to 10 months in prison as part of her plea.
Huffman is among 14 parents who have said they would plead guilty in the scam. He admitted to paying $250,000 to get his son into the University of Southern California as a fake water polo recruit. She was accused of agreeing to pay William "Rick" Singer, the accused mastermind of the scheme, thousands of dollars to help her daughter with her college admissions process.
Some parents have made a decision to fight the charges. According to an indictment, Loughlin and her husband, Mossimo Giannulli, paid Singer $500,000 to establish false athletic profiles for their two daughters.