Numerous infected people had bought large trays or chubs of ground beef from grocery stores and used the meat to make dishes like spaghetti sauce and Sloppy Joes, the agency said.
It comes amid an outbreak of E. coli-related sickness affecting 156 people in 10 states, all after eating ground beef.
The majority of the cases occurred in Tennessee, Kentucky and Georgia, but consumers also became ill in Florida, Illinois, Indiana, Minnesota, Mississippi, Ohio and Virginia.
The ground beef in 24-pound packages was shipped in cardboard boxes marked "Ground Beef Puck" with "Use Thru" dates of 4/14/19, 4/17/19, 4/20/19, 4/23/19, 4/28/19, and 4/30/19, the USDA says.
At least twenty people have been hospitalized from possibly consuming tainted ground beef, however, no deaths have been reported. "At this time, there is no definitive link between this positive product and the ongoing E. coli O103 outbreak". Orange, Florida, and Norcross, Georgia, which sent it to restaurants.
According to the U.S. Department of Agriculture's Food Safety and Inspection Service, "the bulk raw ground beef was produced on October 30-31, 2018 and November 1, 2018".
No supplier or brand of ground beef has been conclusively linked to the ongoing outbreak, the CDC says.
The recalled products all feature the number EST. At the time, it said the outbreak involved 109 cases of illnesses in six states.
The symptoms of an E. coli infection include painful and severe abdominal cramps, diarrhea that may be bloody, and vomiting. Most people recover in five to seven days.
Consumers may continue eating ground beef, according to the CDC, but should handle it safely and cook it thoroughly to avoid foodborne illness. An E. coli O103 infection is more hard to diagnose than the more common E. coli O157:H7 infection because most clinical labs do not test for non-O157 Shiga toxin-producing E. coli infections.