In a tweet, President Trump thanked Mr Zinke for his service, saying he had "achieved much during his tenure".
It would be an understatement to say that environmentalists and Democratic politicians were pleased to see Zinke go, and they quickly took to the internet to let him know it.
The 57-year old Zinke has yet to speak on this matter.
But some conservation and environmental groups argue those moves have come at a cost to the environment, wildlife and the future climate.
Zinke will depart from his administration at the end of the year.
Ryan Zinke is out as secretary of the interior.
"Ryan Zinke's tenure at Interior was a never-ending stream of awful management decisions, increased exploitation of public lands, reduced protections for wildlife, total disregard for the work of scientists, and an alarming number of ethical lapses", Rep. Don Beyer tweeted.
"The swamp cabinet will be a little less foul without him", Schumer said. The Department of Interior's inspector general launched several investigations targeting the former Navy SEAL and Montana congressman, including complaints of improper use of government resources.
Zinke has denied wrongdoing.
Over the last few months, however, reports emerged that even the White House was beginning to rethink Zinke's ongoing place within the administration.
"Secretary Zinke has been a shameless handmaiden for the special interests".
There is talk that deputy David Bernhardt will replace him. "The role is typically filled by Western politicians who have experience navigating the vast federal lands". By contrast, Zinke "pushed the largest reduction of. treasured public lands in American history", proposed opening most of America's coasts to offshore oil drilling and "played a shell game" with wildfire budgeting during two of the most expensive wildfire seasons in USA history, Wyden said.
The Associated Press reported in December 2017 that Zinke had taken three unnecessary helicopter rides worth $53,000, including one to take a horseback ride with the vice President.