See, while marrying Prince Harry has given the former Suits star an global platform, it's also been something of a mask when it comes to politics.
But if Markle wants advice on how to ride out the media storm, she may want to consider what another person in the public glare - former American First Lady Michelle Obama - has provided.
Yesterday, 5 December, 37-year-old pregnant Megan Markle appeared at the event, "Association of Commonwealth universities", which was also attended by leaders, academics and students of British universities.
Reports of a growing rift between the Duchess of Cambridge and the Duchess of Sussex have reached fever pitch in recent days. In July, Serena had support from the Duchess and her sister-in-law Kate Middleton during Wimbledon.
Wearing a black outfit, the 37-year-old Duchess of Sussex attended the Association of Commonwealth Universities' gathering of university leaders, academics, and global scholarship students at King's College London on Wednesday.
Kensington Palace insists that the Cambridges were not expected, but a source admitted that it "was a shame" they didn't attend the meeting or the subsequent party.
When asked if they had been resolved, William laughed and replied: 'We don't know'.
Harry and Meghan's move from London to Frogmore House in Windsor, Berkshire, was reported to have reflected the discord between the royal wives.
Speaking to BANG Showbiz, she said: "I mean, I've never called myself a film actor, I'm just an actor".
It was the cutest way to give a nod to her BFF from across the globe, wouldn't you agree?