She saved four of six break points and hit 22 winners to Wang's 15 as she closed out victory in 83 minutes.
She then defeated Caroline Garcia in her second match, the Frenchwoman going on to beat Sabalenka in their clash to allow Barty to sneak into the semi-finals.
China's top-ranked player, Wang had a tough time with clinging to her serves.
"There's a tendency to have long games, whether they're return or service games".
Up next, she'll take on Ashleigh Barty, a fellow first-time Zhuhai finalist, for a chance to lift the trophy.
Also, she bags $2.35 million from the tournament for the 12 best-ranked players who failed to qualify for the WTA Finals.
"My goal is to stay top 20 and try and consolidate as best I can".
The writing looked to be on the wall when Barty fell a set and a break down, but she demonstrated admirable resilience to force what proved a one-sided decider.
"It's been a phenomenal year and I'm looking forward to a bit of holiday and then getting ready for the Australian summer".
China's number one did not initially qualify for the tie, but took advantage of a late call-up following an injury to Madison Keys and cruised to victory over double grand slam victor Muguruza. Wang, who claimed the last direct qualifying spot with an annual points total of 2155, bounced back by coming from a set down to defeat Keys in the second round-robin match in the Azalea Group. Wang trails Barty 0-1 in the pair's head-to-head record after falling in straight sets against the Australian in Strasbourg earlier this year.
"I was just called upon yesterday and I won yesterday".