The massed ranks of Egypt made sure Uruguay barely threatened their less illustrious opponents in a cautious first-half, with their rigid defending forcing strike duo Suarez and Edinson Cavani to repeatedly drop deep to build up attack.
Uruguay coach Oscar Tabarez, meanwhile, has selected star strikers Luis Suarez and Edinson Cavani in the first XI, while Atletico Madrid defenders Diego Godin and Jose Gimenez, and ex-Barcelona man Martin Caceres, line up in defence. "I can nearly assure you 100% he'll play", coach Cuper had told the press on the eve of the much-anticipated clash.
Cuper said after the match that he expects Salah to feature against the hosts and, on this evidence, they badly need him.
Uruguay´s deserved last-gasp victory leaves them and Russian Federation in early control in Group A after the hosts´ 5-0 mauling of Saudi Arabia in the tournament opener on Thursday.
Here's how to watch Uruguay vs. Egypt online.
Gimenez's goal took Uruguay level on points with Group A leaders Russian Federation and boosted their chances of making the knockout stages for the third successive World Cup after reaching the semi-finals in 2010 and last 16 in 2014.
With Egypt settling for a bore 0-0 draw against Ireland before losing 1-0 to England to suffer a first-round exit at the 1990 Italy finals, the stage was set for the former midfielder to boast about the solitary goal for years and years.
The forward was in a race against time to be ready for Egypt's opener against Uruguay but Cuper said on Thursday there was nothing stopping him from playing.
For Uruguay, Suarez had a disappointing match with several missed opportunities.
Egypt were playing their first World Cup match since 1990 and looked set to pull off a notable result only for Jose Gimenez to head the victor from a late free-kick.
"We have enthusiasm and the seriousness to make an excellent match", Cuper said.
"Some people are saying that we will go there, play three matches and return home".
Traditional World Cup broadcaster SBS has a much-reduced role at this year's event, further angering fans.
Uruguay's best chances fell to Luiz Suarez who failed to convert any of the three clear-cut chances that came his way.