In the last few seasons, it has become de rigueur for clubs who have unsafe attacking potentials to be closed out by oppositions at home.
Leicester started on the front foot and put Tottenham under some early pressure.
The breakthrough did arrive 13 minutes in, though, with Vardy hooking Marc Albrighton's cross over the head of Lloris on the volley for his seventh goal of the campaign.
Spurs could have levelled nearly instantly but were left disappointed as Dele Alli ended a counter attack with a tame shot at Kasper Schmeichel, something the visitors would be made to pay for before half-time. The Dane made a similar save just after the half-hour mark to deny Dele Alli.
Leicester have the lowest passing accuracy in the Premier League this season - 71.8%, while they do not fare all that much better in terms of average possession either (39.9%).
In an effort to hold onto the point Puel replaced Riyad Mahrez with Ben Chilwell with 20 minutes remaining at the London Stadium, a decision that frustrated the Algeria global. It was a trademark finish from the Algerian.
There was then half a chance for Kane, who cut back inside and curled the ball over the bar from inside the box, but the second goal of the match would fall the hosts' way in first-half stoppage time.
Mauricio Pochettino and Tottenham now had it all to do in the second half if they harbored hope of returning to north London with anything.
Christian Eriksen should have pulled a goal back but uncharacteristically skewed his shot well wide from just six yards out.
Lamela came on for his first appearance in 13 months.