"Is the administration aware of who the other three or four campaign individuals who were referenced in that Papadopoulos plea were, and are any serving him or advising him in the administration?" the reporter asked.
The guilty plea by Mr. Papadopoulos and a 20-count indictment against Paul Manafort, a former Trump campaign chairman, gave special counsel Robert Mueller's Russian Federation probe momentum this week and put the White House on defense against allegations of collusion with the Kremlin during the 2016 presidential race.
According to sources close the president who spoke with The Washington Post, Trump frustrated his staff by being late to work at the Oval Office.
But the bigger story came later yesterday when it was revealed that former policy adviser George Papadopoulos had pleaded guilty to lying to the FBI during the Russian investigation.
She was responding to a volley of questions on the surrender of Paul Manafort, Trump's former campaign manager, who has been indicted on 12 counts by a special counsel investigating into alleged Russian interference into last year's presidential elections.
Sanders was also asked how she could "describe Papadopoulos as having a limited role when there's a photograph of [him] sitting at a table with then-candidate Trump at a national security meeting".
In fact, Papadopoulos was contacted after he learned he'd be joining the campaign, and the professor only mentioned the "thousands of emails" after he'd been on the Trump campaign for more than a month.
Papadopoulos' lie to Federal Bureau of Investigation agents detailed the nature of his interactions with "foreign nationals" who he believed to be closely connected to senior Russian government officials.
A Trump campaign supervisor encouraged Papadopoulos to make the trip "if it is feasible" on August 15, 2016.
She reiterated that the "real collusion scandal" involves the Clinton campaign, Fusion GPS and Russian Federation working to "smear" Trump.
Sanders downplayed Papadopolous' role within the campaign, saying the indictment is over his "failure to tell the truth", not campaign activities.